General Surgery Specialist Prof. Dr. Fahri Yetişir gave information on the subject. Many hormones play an active role in maintaining the sugar balance in the human body. The most important of these is the hormone called insulin. Insulin is secreted from the pancreas and adjusts the blood sugar level. In obese people, some hormones secreted from fat cells reduce the effect of insulin on cells and interruptions occur in the transition of sugar from blood to cells. As a result, the sugar concentration in the blood increases. This condition is called insulin resistance. People with this insulin resistance need much more insulin than the insulin normally needed for sugar regulation.
The biggest factor in the formation of type 2 diabetes is insulin resistance. Insulin released to lower blood sugar in normal people is too insufficient to lower blood sugar in the presence of this resistance and cannot regulate blood sugar. On top of that, the pancreas secretes more insulin. In obese patients with insulin resistance or type 2 diabetes patients, much more insulin is often secreted and blood insulin levels are generally high. As obesity increases, insulin resistance increases, as insulin resistance increases, the amount of insulin required increases, up to a certain point, the pancreas compensates for this situation by overworking. In order to correct diabetes over a certain stage, external antidiabetic drugs or insulin support is required. The high level of insulin in the body stimulates the hunger center, causing you to eat more and make your obesity worse. That's why these obese type 2 diabetics remain in a vicious circle that is difficult to break. It is really difficult for these patients to comply with their diets and control their weight and sugar, and it requires a very hard effort. In obese patients with type 2 diabetes, especially if diabetes cannot be controlled despite drug therapy, a suitable metabolic surgery option can be offered after the patient is evaluated very well today.