Stating that diabetes is a metabolic disease that occurs as a result of the pancreas' inability to produce enough insulin hormone or the body's inability to use the insulin it produces sufficiently, Prof. Dr. Serdar Ceylaner stated that there is a strong relationship between diabetes and genetics.
Private Intergen Genetic Diseases Evaluation Center founding physician Prof. Dr. Serdar Ceylaner said, “Blood sugar tests are generally used to diagnose diabetes. In addition, when the diagnosis is finalized, it is necessary to investigate the causes, since genetic factors are known to play an important role in the development of diabetes. Some genetic factors can increase insulin resistance or decrease insulin production. "These factors can increase the risk of diabetes and may be the cause of diabetes in some people," he said.
Stating that there may be some diseases that mimic diabetes, Prof. Dr. Serdar Ceylaner said:
“Recurrent low blood sugar (hypoglycemia) can be seen in various genetic diseases. In addition, diseases that cause diabetes, such as MODY and mitochondrial diseases, often show symptoms similar to type 1 or type 2 diabetes. Therefore, the genetic factors of a person diagnosed with diabetes should also be evaluated. Genetic test results can provide important information for the patient's treatment plan and lifestyle changes.“
prof. Dr. Serdar Ceylaner stated that there is a strong relationship between diabetes and genetics and said, “Diabetes is a complex disease that can be affected by more than one genetic factor. Depending on the type of diabetes, it is associated with different genes. Type 1 diabetes is an autoimmune disease that results in a decrease or cessation of insulin production as a result of destruction of the beta cells of the pancreas. These patients may encounter some new autoimmune diseases in their future life. Type 2 diabetes is a disease that causes insulin resistance and the inability of the pancreas to produce enough insulin. Type 2 diabetes occurs as a result of the interaction of many genetic factors. Gestational diabetes is a type of diabetes that occurs during pregnancy and is associated with many risk factors, including genetic factors. In conclusion, different types of diabetes are associated with different genetic factors, and understanding these factors can help us better understand the development of diabetes and plan its treatment more effectively. With the development of technologies and devices in the field of genetics in our country, methods such as whole exome sequencing (WES) are helpful in the evaluation of many genes associated with diabetes. he said.