Which vaccine should be given during pregnancy and when?

Which vaccine should be given and when during pregnancy
Which Vaccine Should Be Given During Pregnancy?

Acıbadem Dr. Sinasi Can (Kadıköy) Hospital Gynecology and Obstetrics Specialist Assoc. Dr. Şafak Yılmaz Baran gave information about the angles made during pregnancy.

The American Society of Obstetrics and Gynecology (ACOG) routinely recommends tetanus, diphtheria, pertussis, hepatitis B and influenza vaccines for all pregnant women. These vaccines, which have a good safety profile in pregnancy, can provide passive protection to the newborn and do not cause abortion. Gynecology and Obstetrics Specialist Assoc. Dr. Şafak Yılmaz Baran explains the vital importance of vaccinations during pregnancy as follows:

“Influenza”

Influenza vaccine is another important vaccine recommended during pregnancy. Assoc. Dr. Şafak Yılmaz Baran pointed out that influenza infection has a different feature from hepatitis B infection, as it can progress more severely during pregnancy, and said, "Because influenza can cause an increase in lung and heart problems, hospitalization and miscarriage in the mother." In addition to these, Assoc. Dr. In this way, Şafak Yılmaz Baran provides protection not only to expectant mothers but also to newborns under 6 months old. The General Directorate of Primary Health Care Services of the Ministry of Health recommends influenza vaccination to pregnant women after the 14th week of pregnancy, during the influenza season (in September-April).

“Covid-19 vaccine”

In the studies conducted in the Covid-19 pandemic, it was observed that this infection was more severe in expectant mothers compared to non-pregnant women, and as a result of the studies; Stating that inactive Covid-19 vaccine applications have been found to be effective and safe for expectant mothers and newborns at every stage of pregnancy, Assoc. Dr. Şafak Yılmaz Baran said, “For this reason, Covid-19 vaccine is recommended for expectant mothers in line with the recommendation of the Ministry of Health and Obstetrics and Gynecology Associations. There is no evidence that it is necessary to delay the Covid-19 vaccine until after the first 12 weeks of pregnancy. Therefore, the vaccine can be administered at any stage of pregnancy. One dose of Covid-19 vaccine provides good protection against the original alpha variant, but two doses are required to maintain good immunity with the delta variant of the virus. The second dose is administered 8 weeks after the first dose. A dose booster (third dose) is recommended to provide the best protection against the Omicron variant.” said.

“Tetanus-Diphtheria vaccine”

Tetanus infection; It can develop as a result of injuries, bites, traffic accidents and burns during pregnancy or as a result of cutting or dressing the umbilical cord of the baby (especially in home births) with an unhygienic tool such as a knife. Dr. Şafak Yılmaz Baran said, “Thanks to vaccination, the severity of tetanus infection that can occur during pregnancy decreases, and the risk of premature birth and stillbirth that may develop due to this decreases. In addition to these, neurological problems that may develop in the baby can also be prevented. Diphtheria is a disease that can lead to fatal consequences in the respiratory tract. The diphtheria toxoid vaccine is administered together with the tetanus vaccine in the vaccination calendar since childhood. However, since life-long immunity cannot be provided with vaccination in childhood, the application is repeated with tetanus vaccine in case of pregnancy.

According to the tetanus-diphtheria vaccine calendar; Assoc. Dr. Şafak Yılmaz Baran said, “The second dose is administered at least 4 weeks after the first dose, thus providing 4-4 years of protection. With this; 1 years after the third dose administered at least 3 months after the second dose, and 2 years with the vaccine administered at least one year after the third dose or in the next pregnancy. Again, according to the vaccination calendar; Protection is provided throughout the childbearing age with the vaccine administered at least one year after the 6th dose or in the next pregnancy. In women who were previously vaccinated with five full doses, if no additional dose has been given in the last 3 years, a single dose vaccination is sufficient, preferably between 5-3 weeks of pregnancy. she told me.

"Hepatitis B vaccine"

Assoc. Dr. Şafak Yılmaz Baran said, “Hepatitis B infection during pregnancy is not expected to be more serious than the normal population. However, there is a risk of transmission of infection to the newborn. Therefore, vaccination of expectant mothers who have not previously been immune to hepatitis B infection during pregnancy reduces the risk of transmission of hepatitis B virus, which can cause serious problems in the newborn. The vaccine administered at 0, 1 and 6 months of pregnancy protects both the mother and the baby after birth.” he said.

“Pertussis vaccine”

Assoc. Dr. Şafak Yılmaz Baran said that for this reason, additional doses are recommended for the high-risk patient group (healthcare workers, people living with immunocompromised people, living or working with small children). Assoc. Dr. Şafak Yılmaz Baran noted that pertussis vaccine is recommended to be administered after the 6th month of pregnancy, to protect the baby to be born, so that the baby can be provided with passive protection in the early stages.

“Beware of these vaccines during pregnancy!”

Not recommended during pregnancy: Live vaccines have a risk of infecting the fetus in the womb. Therefore, oral polio, measles-rubella-mumps, shingles, varicella and tuberculosis vaccines are not recommended during pregnancy as they are live vaccines. Another vaccine that is not recommended during pregnancy is the Human Papilloma Virus (HPV) vaccine. Due to the scarcity of studies on the HPV vaccine, it is not recommended to be administered during pregnancy, although it has been shown in limited studies to be safe.

Applied in case of necessity: Pneumococcal, hepatitis A, meningococcal, inactivated polio and hemaphylus influenza vaccines; Among the vaccines recommended to be administered according to various risk factors, necessity conditions and age factor. However, the safety of these vaccines for the fetus is not clear. For example, pneumococcal vaccine and hemaphylus influenza can be administered in high-risk individuals such as patients with chronic diseases and weakened immune systems, if necessary.

It is completed before pregnancy: Women who want to become mothers are checked for immunity to infections such as measles, mumps, rubella and chickenpox. If there is no immunity, pre-pregnancy vaccinations are completed. Because, if these diseases develop in expectant mothers who have not encountered these infections before or who are not immune, pregnancy and the baby to be born can be adversely affected.

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