Infections in the Body Lead to Multiple Organ Failure

The defense system response, which occurs as a result of bacterial, viral or fungal infections triggering inflammation, causes damage to organs in the body. Stating that the physiological functions of the body are impaired in the table called sepsis, experts draw attention to the fact that single or multiple organ failure may occur if the people with the diagnosis are not treated correctly and adequately. Experts emphasize that multiple organ failure is a condition in which multiple organs and systems are affected, and if left untreated, it leads to death.

Üsküdar University NPİSTANBUL Brain Hospital Internal Medicine Specialist Assist. Assoc. Dr. Ayhan Levent touched upon the factors leading to multiple organ failure and the importance of early treatment.

Inflammation damages organs

Stating that bacterial, viral or fungal infections can turn into a life-threatening disease in the whole body, Internal Medicine Specialist Assist. Assoc. Dr. Ayhan Levent, “Infection triggers inflammation in the body. If the inflammation is too much, the resulting defense system response can affect the organs and cause damage. This picture, which infectious diseases develop throughout the body, is defined as sepsis. When sepsis is not treated, the production of immune system elements further increases, disrupting the body's physiological functions and causing disruptions in all systems of the body, especially the cardiovascular system. We frequently encounter findings such as low blood pressure, liver and kidney failure, respiratory failure and coagulation disorder in patients with multiple organ failure. said.

Sepsis must be treated correctly

Dr. Ayhan Levent said that when sepsis is detected in a patient, it should be treated quickly and continued as follows:

“If people diagnosed with sepsis are not treated correctly and adequately, the condition can progress to single/multi-organ failure. If organ failure has occurred, the new name of the disease is severe sepsis. In severe sepsis, low blood pressure and renal failure may occur despite adequate fluid and drug therapy, which may lead to septic shock. In septic shock, which occurs with the progression of sepsis, a serious decrease in blood pressure is observed with the effect of the cardiovascular system. As a result, in case of insufficient blood supply to the organs, multi-organ failure develops as other organs are affected along with circulatory failure. This causes serious death. We can say that multi-organ failure is very common among the causes of death in the intensive care unit.”

Delay in treatment results in death

Emphasizing that it is very important to diagnose multiple organ failure in a short time and to start treatment early, Assist. Assoc. Dr. Ayhan Levent, “Early diagnosis and intervention, which is important in every disease, is very critical for patients with multi-organ failure. Multiple organ failure is a condition in which multiple organs and systems are affected, and if left untreated, patients die. The first affected system is generally the respiratory and cardiovascular systems, and accordingly, the amount of oxygen in the patients decreases. The work of the heart is disrupted and the disruption in the transport of blood to the organs causes the clean blood not to be transmitted correctly and the formation of clots in various places. These clots may cause occlusion of the vessels going to other organs and may pave the way for the development of a picture in which all body functions are impaired. For this reason, it is vital to prevent multi-organ failure before it occurs, if possible, and to recognize and treat it at an early stage.” said.

Covid-19 can also lead to organ failure

Internal Medicine Specialist Assist. Assoc. Dr. Ayhan Levent said that infections such as pneumonia, urinary tract infection, heart attack, heart failure, gastrointestinal bleeding, pancreatitis, trauma, burns, toxic agents, major surgical operations, Covid-19 are the main conditions that lead to multi-organ failure. completed:

“In multi-organ failure, a total of 6 organ systems are evaluated, including respiratory, cardiovascular, liver, hematological, kidney and glaskow coma score. Respiratory cardiovascular and glaskow coma scales are parameters measured by physical examination and vital signs. Dysfunction of other organs is understood according to the level of markers in the blood that show the metabolic state of these organs. Covid-19 can also cause multi-organ failure due to the increase in the inflammatory response in the background of sepsis. The most important cause of death due to Covid 19 is multi-organ failure.”