In the cartilage tissue in joints such as knees and hips, wear and tear can develop with age, excessive damage due to wear and can cause pain and limitation of movement in the joints. In the past, it was generally predicted that after the knee and hip joint cartilage was damaged, it would not regenerate itself. However, nowadays, it is possible to prevent cartilage damage and joint calcification with medical advances in stem cell therapy.
A study at Stanford University found a new way to regenerate and repair cartilage with stem cells. Known for his work on Stem Cell Therapy on the subject, Dr. Yüksel Büküşoğlu is telling.
Dr. Yüksel Büküşoğlu stated that joint cartilage is very important to ensure our movements, and that the treatments that prevent and renew the damage to the knee and hip cartilage tissue without surgery gain great importance. Dr. Büküşoğlu ”“ A new study at Stanford University found a new chemical signaling pathway that directs stem cells to regenerate and repair joint cartilage. Researchers have found a way to influence stem cells to produce normal cartilage. In this study, the researchers first used a molecule called BMP2 to initiate bone tissue formation. Later, they halted the bone formation process halfway through another molecule called VEGF. As a result of this process, the formation of cartilage tissue with the same type of cells and the same mechanical properties as natural cartilage was observed. This new cartilage tissue was found to have the potential to restore mobility and significantly reduce knee and hip pain in people with joint calcification, or osteoarthritis. With the innovations in stem cell therapy, it is possible to prevent osteoarthritis, namely joint calcification disorders, by regenerating and rejuvenating the cartilage tissue in knee and hip joint arthritis without completely disrupting it, ”he said.